Search the EPA Research Database

Project Search Result

Project Code [2007-PhD-ET-8]

This information is correct as of today and is updated from time to time by the EPA to reflect changes in the management of the project. Please check back regularly for updates.

Project title

Elucidation of global regulatory signalscontrolling a biotechnologically significant pathway for the degradation of styrene,

Primary Funding Agency

Environmental Protection Agency

Co-Funding Organisation(s)

n/a

Lead Organisation

University College Cork (UCC)

Lead Applicant

Alan Dobson

Project Abstract

Pseudomonas putida CA-3 is a bioreactor isolate capable of complete degradation of the toxic pollutant styrene, generated by the polymer processing industry. As a result, the potential exists for the application of this organism in whole cell based biotechnological approaches to treat stored styrene waste. However, despite extensive characterisation of the physiology and molecular biology of this pathway by our group, one aspect which is poorly understood is how the pathway is integrated into overall carbon metabolism. This study seeks to address this issue of global regulation of the sty operon by conducting functional genomic analyses and gene expression profiling to identify regulators involved in catabolite repression of the pathway

Grant Approved

�87,810.00

Research Hub

Green and Circular Economy

Research Theme

Waste and Resources Management

Start Date

23/06/2008

Initial Projected Completion Date

23/06/2011