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Project Code [2007-PhD-ET-8]
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Project title
Elucidation of global regulatory signalscontrolling a biotechnologically significant pathway for the degradation of styrene,
Primary Funding Agency
Environmental Protection Agency
Co-Funding Organisation(s)
n/a
Lead Organisation
University College Cork (UCC)
Lead Applicant
Alan Dobson
Project Abstract
Pseudomonas putida CA-3 is a bioreactor isolate capable of complete degradation of the toxic pollutant styrene, generated by the polymer processing industry. As a result, the potential exists for the application of this organism in whole cell based biotechnological approaches to treat stored styrene waste. However, despite extensive characterisation of the physiology and molecular biology of this pathway by our group, one aspect which is poorly understood is how the pathway is integrated into overall carbon metabolism. This study seeks to address this issue of global regulation of the sty operon by conducting functional genomic analyses and gene expression profiling to identify regulators involved in catabolite repression of the pathway
Grant Approved
�87,810.00
Research Hub
Green and Circular Economy
Research Theme
Waste and Resources Management
Initial Projected Completion Date
23/06/2011