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Project Code [2006-PhD-ET-10]
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Project title
Environmental issues relating to the manufacture of antisense-based products of pharmaceutical biotechnology
Primary Funding Agency
Environmental Protection Agency
Co-Funding Organisation(s)
n/a
Lead Organisation
University of Limerick (UL)
Lead Applicant
Gary Walsh
Project Abstract
Several antisense drugs (chemically modified RNA/DNA which downregulate specific disease-related genes) will shortly gain approval for medical use. Their unique manufacturing routes and bioactivity raises unique unaddressed environmental issues. This project seeks to establish the environmental impacts associated with the product lifecycle of an antisense therapy and to develop technical methodologies to evaluate and treat specific manufacturing waste streams rendering them free of active antisense product. It will broaden the Irish environmental research base generate environmental expertise in this cutting edge area and provide a framework to assist environmental agency personnel in the formulation of BREF documentation for antisense-based pharmaceutical manufacturing.
Grant Approved
�84,136.00
Research Hub
Green and Circular Economy
Research Theme
Waste and Resources Management
Initial Projected Completion Date
21/11/2012