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Project Code [2008-PhD-EH-3]

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Project title

Genetic methods to improve Cr(VI) bioremediation in groundwater

Primary Funding Agency

Environmental Protection Agency

Co-Funding Organisation(s)

n/a

Lead Organisation

Dublin City University (DCU)

Lead Applicant

Enrico Marsili

Project Abstract

Cr(VI) contamination of groundwater and soils is a primary public health concern in Ireland. Bioremediation is an environmental-friendly salternative for Cr(VI) removal from groundwaterand soils, but Cr(VI) toxicity limits the efficiency of bioremediation. We will use for the first time genome shuffling techniques to improve Cr(VI) tolerance and Cr(VI) reduction capability of the strict anaerobic bacterium Geobacter metallireducens. We will investigate the mechanism of Cr(VI) reduction in the resulting G.metallireducens mutants through an innovative electrochemical approach. Finally, we will test the best performing mutants in a bench-scale Cr(VI) bioremediation process.

Grant Approved

�92,000.00

Research Hub

Healthy Environment

Research Theme

Impacts on Aquatic Ecosystems & Human Health (including Drinking Water)

Start Date

11/09/2008

Initial Projected Completion Date

11/09/2011