Search the EPA Research Database
Project Search Result
Project Code [2020-NC-PhD-12]
This information is correct as of today and is updated from time to time by the EPA to reflect changes in the management of the project. Please check back regularly for updates.
Project title
Studies on Metabolites of Common Antibiotics in the Development of Antimicrobial Resistance (AM-AMR)
Primary Funding Agency
Irish Research Council
Co-Funding Organisation(s)
Environmental Protection Agency
Lead Organisation
Technological University Dublin (TU Dublin)
Lead Applicant
Fintan Kelleher
Project Abstract
The first aim of this project is to synthesise, purify and characterise the main metabolites (human, veterinary and environmental) of two very widely used and important classes of antibiotics, i.e. fluoroquinolones and sulfa drugs. The second aim is to expose a number of clinically important bacterial species to these antibiotic metabolites, where the bacteria chosen are susceptible to the original antibiotics, and then determine if any of the synthesised metabolites generate bacterial resistance to the parent antibiotic. The results obtained could have far-reaching consequences for wastewater treatment in general, especially for the removal of both antibiotics and their many metabolites from water, both in Ireland and throughout the world.
Grant Approved
�96,000.00
Research Hub
Natural Environment
Research Theme
Natural capital and ecosystem services including soils and biodiversity
Initial Projected Completion Date
30/09/2024